Details

Subject Count: 2994

Primary Site: Breast

Image Modalities: MG

Cancer Type(s): Breast Cancer

Species: Human

Supporting Data: Software/Source Code

DOIs

VICTRE original data:

Description

The VICTRE Trial: Open-Source, In-Silico Clinical Trial For Evaluating Digital Breast Tomosynthesis

A total of 2986 subjects, with breast sizes and radiographic densities representative of a screening population and compressed thicknesses from 3.5 to 6 cm, were simulated and imaged on in-silico versions of DM and DBT systems using fast Monte Carlo x-ray transport. Images were interpreted by a computational reader detecting the presence of lesions. The in-silico trial (VICTRE) was designed to replicate a comparative trial from a previous regulatory submission. The endpoint was the difference in area under the receiver-operating-characteristic curve between modalities (delta-AUC) for lesion detection.

See the VICTRE Collection wiki page to learn more about the images and to obtain any supporting metadata for this collection.